BRCA1/2 tumor testing (AZ)

Code: 4951

The availability and turnaround time of this test should be confirmed with the unit before collection.

Method

NGS / MLPA / PCR

Collection requirements

Paraffin-embedded biopsy, sectioned and mounted on slides + EDTA: Blood (6 mL)

Sample stability

Paraffin-embedded biopsy - room temperature; EDTA: Blood (6 mL) - refrigerated at 2-8 °C

Turnaround time

15 working days

Preparation and notes

IMPORTANT: 1) Cut and send 5 tissue sections 5 µm thick from a paraffin-embedded block containing the tumor area selected for analysis: the selected area must be at least 1cm2 (per section) and tumor tissue must represent at least 70% of the cells; samples must be sent together with a serial section stained with hematoxylin and eosin with the selected tumor area marked. This information is crucial for the correct interpretation and integration of the results; if any of these criteria cannot be met, please contact the laboratory to assess the feasibility of the analysis before sectioning the samples. 2) Collect 6 mL of peripheral blood into two EDTA tubes.