Signatera (ctDNA)

Code: 3399

The availability and turnaround time of this test should be confirmed with the unit before collection.

Method

Next-generation sequencing (NGS) + CNVs

Collection requirements

Histological material representative of the invasive tumor [1 paraffin block] and Blood [Streck Cell-Free DNA tube (10 mL)]

Sample stability

Refrigerated at 2-8 °C

Turnaround time

30 working days

Preparation and notes

IMPORTANT: 1. 5 sections with >70% tumor area are required, ideally without necrotic areas, sent in one or more properly labeled Eppendorf tubes (1.5-2 mL). 2. Alternatively, send the sample from the original block. 3. The sections or block must be sent together with a serial section stained with hematoxylin and eosin. 4. Send the pathology report for the specimen(s) to be studied. 5. Paraffin blocks and/or paraffin curls must be sent to the laboratory properly packed in a sealed envelope. Sections must be sent to the laboratory within 5 days of cutting. REQUEST THE SIGNATERA BLOOD COLLECTION KIT FROM THE LABORATORY. Test performed by prior appointment with the laboratory. Note: Attach a copy of the pathology report and the test-specific questionnaire, duly completed and signed.